Determination of potential drug target through Cardiotonic steroids and its Derivatives: an in silico approach
Patel Chirag N , Soni Mehul N , Modi Krunal c , Modi Nainesh R and Pandya Himanshu A
iABCD|Vol 1|Issue 1 |Sep 2016| 01 - 28 |
Cardiotonic steroids (CS) such as ouabain, digoxin, digoxigenin and bufalin, are steroidal drugs prepared from the seeds and dried leaves of the genus Digitalis, and the skin and parotid gland of amphibians, are used as a cardiac stimulant. Increasing the force of contraction of the heart (positive inotropic activity) is very important for most heart failure patients. Cardiac steroids are widely used in the modern treatment of congestive heart failure and for treatment of atrial fibrillation and flutter. In which digoxigenin, a cardenolide type cardiotonic steroid that is one of the major components of the toad venom-prepared traditional Chinese medicine called Ch’an Su or Senso, exhibits a cardiotonic action by inhibiting the membranous Na+/K+-ATPase. Most widely accepted mechanism involves the ability of cardiac glycosides to inhibit the membrane bound Na+/K+-ATPase pump responsible for Na+/K+ exchange. Where, Ouabain isolated from plants is widely used by scientists in in v
Soil Quality Assessment of Selected Agricultural and Forest Fields in Sabarkantha District
PrajapatiDipak, JainNayan and PandyaHimanshu
iABCD|Vol 1|Issue 1 |Sep 2016| 29 - 39 |
Nowadays, there is a great demand for precise, sensitive and adequate indicators for soil quality evaluation. Soil is the main factor which contains the entire feature for floristic growth. It is important for all life over the earth and necessary to analyze not only to understand its importance but also for improvement. Now it is evident that the adequate soil conditions, day by day are decreasing which is detrimental for biodiversity. This will lead to improper output/outcome of soil either for forest needs or for agricultural needs. To increase health or quality of soil, assessment is important. The objective of the study was to assess the quality of soil in response of physical, chemical and microbiological (CFU counts) analyses of agriculture and forest fields of the Sabarkantha district which is the dry deciduous agro-climatic zone of the Gujarat state. Soil sampling was random for both agriculture and forest land. Over all soil nature of the district was sandy loam. Agricultu
Nutrient Management for Enhanced Growth of Catharanthus roseus L.
Pandya Jahnavi, Qureshi Shirin, Mankad Archana
iABCD|Vol 1|Issue 1 |Sep 2016| 40 - 4 6 |
Plants absorb nutrients through the roots and through the foliage. When soil conditions are unfavorable or when micronutrients are needed, it may be desirable to make foliar applications of the plant nutrients. Foliar fertilization entails the application - via spraying of nutrients to plant leaves and stems and their absorption at those sites. The ability of plant leaves to absorb water and nutrients was recognized approximately three centuries ago. Present study shows the effect of foliar application of Boron and Manganese on the growth of Catharanthus roseus L. Boric acid and Manganese sulphate were applied as a foliar spray at different concentrations. Plant height, Root weight, Shoot weight and Number of leaves were monitored during plant development. Results clearly show that foliar application of boric acid and manganese sulphate mixture solution is beneficial for Catharanthus roseus L.
Greenhouse Gas emissions from the field Burning of Crop residues for the state of Gujarat
Parmar Mona and Solanki Hitesh
iABCD|Vol 1|Issue 1 |Sep 2016| 47 - 59 |
The quantity of greenhouse gases emitted and the source responsible for its emission are necessary to determine the solution for climate change and its impact. In Gujarat a large part of crop residue is burnt in the fields since the farmers do not have any worthwhile use of this waste and the combine-harvester leaves, a large part of this residue in the field itself in the form of long stems and the roots. And thus these burnings of crop residue lead to the emission of greenhouse gases. The main objective of this study was to calculate the GHG emissions from the burning of crop residues for the state of Gujarat.CO2, CH4 and N2O emission from crop residue burning were calculated for the year 1980 to 2011 for the state of Gujarat. For each plant gross CO2 equivalent emission and emission intensity (footprint) was determined for 31 years (1980 to 2011) to study an emission trend. As a result, Crop residue burning emissions are increasing by the year, but the emission intensity remains&